hrp0094fc8.6 | Neuroendocrinology | ESPE2021

Efficacy and Safety of Corifollitropin Alfa in Combination with Human Chorionic Gonadotropin for Initiation or Restoration of Puberty in Adolescent Males Aged 14 to < 18 Years with Hypogonadotropic Hypogonadism

Shankar R. Ravi , Shah Suneri , Joeng Hee-Koung , Mendizabal Geraldine , Guan Yanfen , Stegmann Barbara J. , Nieschlag Eberhard , Behre Hermann M. , Swerdloff Ronald S. , Fox Michelle C. , Kaufman Keith D. ,

Background: Combinations of follicle-stimulating hormone (FSH) and human chorionic gonadotropin (hCG) have been successful in treating males with hypogonadotropic hypogonadism (HH). The aim of this study was to investigate the efficacy and safety of corifollitropin alfa (CFA), a long-acting FSH analog, combined with hCG to induce testicular growth and pubertal development in adolescent males with HH.Methods: This was a 6...